AstraZeneca's Crestor trial has been hailed as a huge success for the drug's maker.
The results of the trial were announced today by AstraZeneca (the developer of the drug).
The company's Crestor trial is the first to compare Crestor's cholesterol-lowering drug with a placebo in a single trial.
Crestor is a statin that is prescribed to help people lose their cholesterol. Its maker, AstraZeneca, is not aware of the trial results.
AstraZeneca's Crestor results were published in the November 2007 issue of the New England Journal of Medicine.
It had already been the subject of a press release by the company that said: "The Crestor trial demonstrated that Crestor is more effective in helping people get their cholesterol back on track."
The company has also said it is "working to further evaluate the trial results and make any necessary adjustments to its results."
The Crestor results showed that the drug reduced the risk of heart attacks and strokes by about 25% and by about 40%, respectively.
The trial is expected to be held in May 2008 at the American Heart Association's in St. Louis, Mo.
"We think Crestor is a great medicine for many people with high cholesterol," said Dr. Stevennoter, a member of the steering committee for Crestor.
Crestor was approved by the FDA in the second half of 2006 for people with low to moderate LDL (low-density lipoprotein) cholesterol.
The drug is now the world's second-biggest drug, with sales of $13 billion, according to data from the company's own worldwide market research.
In 2006, Crestor sales were $6.5 billion, while the generic version had $6.2 billion, according to data from the company's own worldwide market research.
The trial was approved by the FDA for a total of 10 years in 2009.
The company was also the world's second-biggest drug maker in 2010. AstraZeneca is expected to launch the first-ever generic version of Crestor in the United States.
The trial will run until November 2009.
| Photo by: AstraZenecaThe results were based on the results of a clinical trial that Crestor was given to participants who had a lower-than-average risk of heart attacks, strokes, and other heart conditions.
The drug was studied by researchers in patients with a history of coronary artery disease, heart attack, or stroke, who had taken it for at least six months before the trial began. The study found that the drug reduced the risk of heart attacks and strokes by about 25% and by about 40%, respectively.
The trial was also the first to compare Crestor with a placebo in a single-blind, randomized trial. The trial was approved in the United States by the FDA in May 2006.
The Crestor results were published in the November 2007 issue of the New England Journal of Medicine.
The study was also the first to compare Crestor with a placebo in a double-blind, randomized trial. The drug was studied by researchers in people with a history of coronary artery disease, heart attack, or stroke, who had taken it for at least six months before the trial began.
The trial was also the first to compare Crestor with a placebo in a double-blind, randomized trial.
NEW YORK--(BUSINESS WIRE)--The Pharmaceutical Research and Manufacturers of America (PhRMA) announced today that its cholesterol drug Crestor will be available at its current pharmacy as a generic drug. The new product is a generic version of the blockbuster cholesterol drug Lipitor.
Crestor, approved by the U. S. Food and Drug Administration (FDA) in April 2007, is a 5-alpha reductase inhibitor used to lower high-density lipoprotein (HDL) cholesterol levels by lowering LDL to 50 mg/dL (mg/dL) and total cholesterol (TC) levels by 3.6 to 10.0 mg/dL. The drug is currently available in a branded pack of 50 tablets for less than $5.
Crestor is the only 5-alpha reductase inhibitor available in the U. with a proven safety profile. This approval allows the drug to remain a cornerstone in the cardiovascular and lipid-lowering treatment market for patients with certain health conditions.
The new product will be available in all pharmacies and online for $2 per tablet.
The drug is currently available in the U. as Crestor (Crestor-5-alpha reductase inhibitor) (Nasal Spray) and Crestor (Crestor-5-alpha reductase inhibitor) (Levoketor). In October 2010, Crestor was approved by the FDA for the treatment of patients with elevated LDL cholesterol (HDL-C) levels. The new product is available in all pharmacies and online for $2 per tablet.
PhRMA also announced today that its cholesterol drug, Lipitor, will be available in the U. as a generic drug.
About Crestor
Crestor, or Crestor-A, is an oral statin treatment for people with high LDL levels that may cause or exacerbate elevated LDL levels. The generic form of Crestor is the brand Crestor-5-alpha reductase inhibitor. The generic is currently approved for use in patients ages 65 years and older. Crestor-A is also approved to treat patients with advanced lipid-lowering treatment. Crestor-5-alpha reductase inhibitors are also used to reduce LDL levels in patients with type 2 diabetes. The product will be available in all pharmacies and online for $2 per tablet.
Crestor is a 5-alpha reductase inhibitor that works by blocking the body's production of a type of hormone called lipase. Lipase is an essential part of the body's lipoprotein metabolism and is responsible for breaking down fat in the body. When the body does not produce enough lipase, it will break down fat again.
The drug will be available in all pharmacies and online for $2 per tablet. Crestor-5-alpha reductase inhibitor is a generic drug approved by the FDA to treat patients with a family history of heart failure or type 2 diabetes. It is also approved to treat the condition of patients who have had at least two failed heart and blood tests. Crestor-5-alpha reductase inhibitors are also used to reduce LDL cholesterol in patients with certain cardiovascular and lipid-lowering treatment conditions.
Crestor is a branded version of the blockbuster cholesterol drug Lipitor, which is the only 5-alpha reductase inhibitor approved by the FDA for the treatment of high LDL levels. Crestor-5-alpha reductase inhibitor is currently approved for the treatment of patients with high LDL levels.
About Rosuvastatin
Rosuvastatin, a generic version of the popular statin medication Lipitor, is a generic medication, manufactured by Merck & Co. It is also approved to treat patients with the condition of hypercholesterolemia. Rosuvastatin is a statin medication that may be used to treat hypercholesterolemia in some people. The use of rosuvastatin is not recommended for patients with diabetes, heart failure, or a family history of liver disease.
About Astra Zeneca Pharmaceuticals
AstraZeneca Pharmaceuticals is a global pharmaceutical company that is engaged in the research, development, manufacture and marketing of prescription medicines. The company is a global leader in prescription medicine and bioscience medicines. Astra Zeneca is a leader in generic medicines.
Crestor, containing rosuvastatin, is a widely prescribed statin medication for managing cholesterol levels. It lowers LDL (bad cholesterol) and triglycerides while raising HDL (good cholesterol), reducing the risk of cardiovascular complications such as heart attacks and strokes. It is a trusted choice for individuals at risk of heart disease or those with high cholesterol.
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References:CRESTOR 40MG TABLET is used in the management of high blood cholesterol levels. It is prescribed when diet and exercise does not result in adequate results. It contains a medicine called which is an anti-hyperlipidemic agent that works by blocking cholesterol production in the body. It also makes your body eliminate lipids particles from the blood.
By reducing blood cholesterol levels, this medicine is helpful is reducing cardiovascular risks and problems in blood circulation across the body. While taking CRESTOR 40MG TABLET, you must follow a cholesterol-lowering diet, lifestyle changes and regular physical activity as instructed by your doctor to achieve better results.
Before taking CRESTOR 40MG TABLET inform your doctor if you have any lung, liver, kidney or heart problems. You must also inform your doctor if you have diabetes, thyroid problems, or a family history of muscle disorders. Do not take CRESTOR 40MG TABLET if you are pregnant or breastfeeding without consulting your doctor.
CRESTOR 40MG TABLET may increase your blood sugar levels, especially in patients who are diabetic. It may also affect the way your liver works and so your doctor will closely monitor your blood sugar levels and liver functions while undergoing therapy with CRESTOR 40MG TABLET as a precaution.
The most common side effects of taking CRESTOR 40MG TABLET are muscle ache, constipation, stomach pain, dizziness, nausea and headache. Inform your doctor if you experience severe unexplained muscle pain, tenderness or weakness along with fever after taking CRESTOR 40MG TABLET.
How should I take CRESTOR 40MG TABLET? CRESTOR 40MG TABLET should be used at a dose of 1 tablet. You can take the medicine with or without food but if you take CRESTOR 40MG TABLET with a high-fat meal, your dose may be higher.The recommended dose in cases of diet and exerciseCombination should be started at 10 mg once daily without first considering the potential side effects. Reduce the dose to once in 3 or 4 doses to 5 mg as needed. Start taking CRESTOR 40MG TABLET at or below the normal dose and treatment period.
Your doctor will decide the maximum dose for you, depending on your specific needs and medical history of you. The maximum recommended dose of CRESTOR 40MG TABLET is 1 tablet per day.
Inform your doctor if you have any lung, liver, or kidney problems. They can prescribe you CRESTOR 40MG TABLET if you experience pain in arms or legs, swelling in legs, lightheadedness, fainting, blurred vision, or fast heartbeat.
You should also be aware that you are unlikely to be able to prevent this condition from recurring while taking CRESTOR 40MG TABLET as side effects may include weight gain, heavy use of prescription medication, and nausea and vomiting.
To treat your condition contact your doctor online at 1-1-1 Trudity online clinic,ixie or I don't want to ask questions.
What laboratory tests do I need for CRESTOR 40MG TABLET? High Folate Levels tests work by detecting high levels ofammuive levels in the blood. High Folate levels test also detect the presence of high levels of High Cholesterol in the blood.Chloramphenicol
The use of this drug is contraindicated because the use of chloramphenicol will increase the effect of Sildenafil by affecting the patient hepatic and intestinal enzyme metabolism. If the action of Sildenafil becomes impaired, the drug will causeermanent changes in the pharmacokinetics of valsartan. Also, the pharmacological effects of Sildenafil should be carefully considered in patients with mild to severe liver impairment.
Isosorbide dinitrate
The use of this drug is contraindicated because the combination of isosorbide dinitrate and tablets of this drug will result in a serious drop in the total blood pressure. Also, the mycoplasma pneumoniae agent will continue to be the cause of pneumonia with the integration of isosorbide dinitrate and tablets of this drug. The combined administration of isosorbide dinitrate and tablets of this drug will result in a serious drop in the total blood pressure. Use of this drug during or within 4 months after the last mycoplasma test is complete may result in a serious drop in the mycoplasma pneumoniae index. Also, the mycoplasma pneumoniae index can be influenced by the dosage and duration of treatment.
Potassium-sparing diuretics
Stade de France Pharmacy